MK-677 vs Sermorelin
MK-677 and Sermorelin are compared here on the things that actually differ between them: what class each belongs to, what each acts on, how each is supplied and what each costs per milligram. Where the registry has no figure for one of them the row is left out rather than filled in.
Side by side
| MK-677 | Sermorelin | |
|---|---|---|
| Class | Orally active ghrelin receptor agonist | GHRH analogue |
| Acts on | A non-peptide growth hormone secretagogue active by mouth, studied for sustained elevation of GH and IGF-1 without injection. | The first 29 amino acids of growth hormone releasing hormone, the shortest fragment retaining full activity at the GHRH receptor. |
| Supplied as | Oral liquid or capsule. | Lyophilised powder or pre-filled pen. |
| Half-life | Approximately 24 hours, which is why it is characterised as once-daily in study design. | Very short, around 10 to 20 minutes. |
| Storage | Cool, dry, out of direct light. | 2-8 C, protected from light. |
| Listings | 1 | 1 |
| Price from | £36 | £70 |
What actually differs
The clearest difference is class: MK-677 is an orally active ghrelin receptor agonist, Sermorelin is a GHRH analogue. They are not supplied the same way. MK-677 comes as an oral liquid or capsule, Sermorelin as a lyophilised powder or pre-filled pen. Half-life differs as well: Approximately 24 hours, which is why it is characterised as once-daily in study design for MK-677 against Very short, around 10 to 20 minutes for Sermorelin.
Quanta Pharma MK-677 (Ibutamoren) 12.5mgin stock£36- SerenQ Sermorelin 15mg Peptide Penout of stock£70
Availability checked 2026-09-09. The product page carries live stock.